A step ahead in
VITAMIN D deficiency1

Simple
Dosing2

Fast
Response3

Effective
Therapy2,3

Predictable
Results4

person mesh

DNORD is indicated for the following2

DNord 255 microgram

Treatment of vitamin D deficiency
(i.e., 25(OH)D levels < 25 nmol/L) in adults

Prevention of vitamin D deficiency in adults with identified risks such as in patients with malabsorption syndrome, chronic kidney disease mineral and bone disorder (CKD-MBD) or other identified risks

As adjuvant for the specific treatment of osteoporosis in patients with vitamin D deficiency or at risk of vitamin D deficiency

1. Charoenngam N and Holick M F: Nutrients 2020, 12, 2097; doi:10.3390/ nu12072097 2. DNORD SPC; https://www.hpra.ie/img/uploaded/swedocuments/Licence_PA23343-001-001_15112022130834.pdf 3. Esteban Jódar E et al; Endocrine Abstracts (2021) 73 AEP83 | DOI: 10.1530/endoabs.73.AEP83 Calcium and Bone 4. Pludowski P et al; Nutrients 2022, 14, 1483. https://doi.org/10.3390/nu14071483

1 DOSE (255mcg),
1 CAPSULE,
1 a MONTH2

Treatment & Dosing

Treatment1

1
Dnord
soft gel capsule,
once a month

Prevention1

1
Dnord
soft gel capsule,
once a month

Adjuvant Treatment1

1
Dnord
soft gel capsule,
once a month
Higher doses may be necessary in some patients after analytical verification of the extent of the deficiency.
Maximum dose should not exceed 1 capsule, once a week.
Once plasma levels of 25(OH)D are stabilised within the desired range, treatment should be discontinued, or the frequency of administration lowered.
Should not be administered with a daily frequency.
must be swallowed whole
can be taken with water
can be taken any time of the day
is reimbursed under the GMS and Community Drugs Schemes and is available in packs of 10 soft capsules for €16.32
1. DNORD SPC; https://www.hpra.ie/img/uploaded/swedocuments/Licence_PA23343-001-001_15112022130834.pdf

Clinical Data

avoids liver metabolism1

is faster and more effective
than Vitamin D3 at increasing serum
25(OH)D concentration2,3

Study in Postmenopausal Women
bullet-point

59% of calcifediol patients (n=200) reached 25(OH)D levels >20ng/ml vs. 34% of cholecalciferol patients (n=98)3

bullet-point

13.5% of calcifediol patients (n=200) reached 25(OH)D levels >30ng/ml vs. 0% of cholecalciferol patients (n=98)3

1. Charoenngam N and Holick M F: Nutrients 2020, 12, 2097; doi:10.3390/ nu12072097 2. Perez-Castrillón et al, Journal of Bone and Mineral Research, Vol. 38, No. 4, April 2023, pp 471-479
3. Perez-Castrillón et al, Journal of Bone and Mineral Research, October 2021, Vol 36, No 10, pp 1967-1978

Role of Vitamin D

Vitamin D deficiency may be associated
with many pathologies1,2

1. Charoenngam N and Holick M F: Nutrients 2020, 12, 2097; doi:10.3390/ nu12072097 2. Report of the Scientific Committee of the Food Safety Authority Of Ireland, 2020

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© 2024 Nordic Pharma. All rights reserved. Date of Preparation: March 2024. Item Code: IE-DNO-2300005.